Ca2+ Current versus Ca2+ Channel Cooperativity of Exocytosis
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چکیده
منابع مشابه
Ca Current versus Ca Channel Cooperativity of Exocytosis
Victor Matveev,1 Richard Bertram,2,3,4 and Arthur Sherman5 1Department of Mathematical Sciences, New Jersey Institute of Technology, Newark, New Jersey 07102-1982, 2Department of Mathematics and Programs in 3Neuroscience and 4Molecular Biophysics, Florida State University, Tallahassee, Florida 32306, and 5Laboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney...
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AIM Neurotransmitter release is elicited by an elevation of intracellular Ca(2+) concentration ([Ca(2+)](i)). The action potential triggers Ca(2+) influx through Ca(2+) channels which causes local changes of [Ca(2+)](i) for vesicle release. However, any direct role of extracellular Ca(2+) (besides Ca(2+) influx) on Ca(2+)-dependent exocytosis remains elusive. Here we set out to investigate this...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2009
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.0263-09.2009